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author:

Xue, Meixiang (Xue, Meixiang.) [1] | Cai, Shuangxi (Cai, Shuangxi.) [2] | Deng, Ye (Deng, Ye.) [3] | Luo, Fang (Luo, Fang.) [4] (Scholars:罗芳) | Huang, Jianhui (Huang, Jianhui.) [5] | Lin, Zhenyu (Lin, Zhenyu.) [6] (Scholars:林振宇)

Indexed by:

EI Scopus SCIE

Abstract:

T-2 toxin, a hazardous mycotoxin often present in cereals and products based on cereals, poses a substantial risk to humans and animals due to its high toxicity. The development of uncomplicated, quick and highly sensitive methods for detecting T-2 toxin is imperative. In this work, a portable sensing system was constructed using water column height as a readout device in combination with a controlled release system, which allows for an accurate quantitative analysis of T-2 toxin without the need for expensive instrumentation or skilled technicians. Hyaluronic acid (HA) hydrogel was constructed by double cross-linked DNA/aptamer hybrids with polyethyleneimine (PEI) and embedded with platinum nanoparticles (Pt NPs). The aptamer specifically bound to T-2 toxin in its presence, resulting in the disruption of the hydrogel and subsequent release of the Pt NPs. These Pt NPs were later mixed with a solution of H 2 O 2 in a confined reaction flask, leading to the decomposition of H 2 O 2 into O 2 . A glass capillary tube containing a column of red water had been inserted into the cap of the reaction flask, and the low solubility of O 2 led to an increase in pressure within the reaction unit, causing the red water column to rise. There is a good linear correlation between the height of the capillary liquid level and the T-2 toxin concentration in the range of 20 ng/mL to 6 mu g/mL. The system has been successfully used to detect T-2 toxin in samples of barley tea and corn.

Keyword:

Hydrogel Portable sensor T-2 toxin Target-responsive Water column height

Community:

  • [ 1 ] [Xue, Meixiang]Putian Univ, Fujian Prov Univ, Coll Environm & Biol Engn,Key Lab Ecol Environm &, Fujian Prov Key Lab Ecol Toxicol Effects & Control, Putian 351100, Fujian, Peoples R China
  • [ 2 ] [Cai, Shuangxi]Putian Univ, Fujian Prov Univ, Coll Environm & Biol Engn,Key Lab Ecol Environm &, Fujian Prov Key Lab Ecol Toxicol Effects & Control, Putian 351100, Fujian, Peoples R China
  • [ 3 ] [Huang, Jianhui]Putian Univ, Fujian Prov Univ, Coll Environm & Biol Engn,Key Lab Ecol Environm &, Fujian Prov Key Lab Ecol Toxicol Effects & Control, Putian 351100, Fujian, Peoples R China
  • [ 4 ] [Deng, Ye]Fuzhou Univ, Coll Chem, Minist Educ Key Lab Analyt Sci Food Safety & Biol, Fujian Prov Key Lab Anal & Detect Food Safety, Fuzhou 350116, Fujian, Peoples R China
  • [ 5 ] [Luo, Fang]Fuzhou Univ, Coll Chem, Minist Educ Key Lab Analyt Sci Food Safety & Biol, Fujian Prov Key Lab Anal & Detect Food Safety, Fuzhou 350116, Fujian, Peoples R China
  • [ 6 ] [Lin, Zhenyu]Fuzhou Univ, Coll Chem, Minist Educ Key Lab Analyt Sci Food Safety & Biol, Fujian Prov Key Lab Anal & Detect Food Safety, Fuzhou 350116, Fujian, Peoples R China
  • [ 7 ] [Lin, Zhenyu]Univ Town Fuzhou, 2 Xue Yuan Rd, Fuzhou 350108, Fujian, Peoples R China
  • [ 8 ] [Huang, Jianhui]1133 Xue Yuan Rd, Putian 351100, Fujian, Peoples R China

Reprint 's Address:

  • [Lin, Zhenyu]Univ Town Fuzhou, 2 Xue Yuan Rd, Fuzhou 350108, Fujian, Peoples R China;;[Huang, Jianhui]1133 Xue Yuan Rd, Putian 351100, Fujian, Peoples R China;;

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Source :

TALANTA

ISSN: 0039-9140

Year: 2024

Volume: 276

5 . 6 0 0

JCR@2023

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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