The　electrostatic　interaction　between　zinc　ions　and　the　host　structure　significantly　limits　the　practicality　of　vanadium-based　cathodes　in　aqueous　zinc-ion　batteries　(AZIBs).　Herein,　an　anion　doping　strategy　is　demonstrated　to　mitigate　electrostatic　resistance　and　steric　hindrance　during　zinc　ion　insertion　by　incorporating　iodine　atoms　into　the　lattice　of　the　cathode　material,　Na2V6O16·3H2O.　Iodine　doping　reduces　the　adsorption　energy　at　the　most　stable　site,　thereby　weakening　the　Zn2+-host　interaction　and　lowering　the　Zn2+　diffusion　energy　barrier,　resulting　in　a　one-order-of-magnitude　increase　in　the　diffusion　coefficient.　Moreover,　the　large　atomic　size　of　iodine　expands　the　host　lattice,　creating　ample　space　for　increased　zinc　ion　storage　capacity,　further　supported　by　the　introduced　oxygen　vacancies.　As　a　result,　the　iodine-doped　Na2V6O16·3H2O　cathode　achieves　an　impressive　specific　capacity　of　528.8 mAh g−1　at　a　current　density　of　0.5 A g−1,　and　retains　262 mAh g−1　after　12,000　cycles　at　a　high　current　rate　of　10 A g−1.　This　work　provides　new　insights　into　the　design　of　high-performance　cathode　materials　for　AZIBs.　©　2025　The　Author(s).　Advanced　Materials　published　by　Wiley-VCH　GmbH.