Conjugated polymer/enzyme/silica hybrid capsules for lactate biosynthesis - Details

author：

Indexed by：

Scopus

Abstract：

Capsules　with　designable　chemical　and　textural　structures　provide　a　universal　and　versatile　platform　for　enzyme　immobilization.　Herein,　a　capsular　biocatalyst　(TpBD　CP@Lactate　dehydrogenase@Silica　capsules,　TLS　capsules)　was　developed　by　entrapping　enzyme　within　the　wall　of　conjugated　polymer　(CP)/silica　hybrid　capsules.　The　porous　wall　of　TLS　capsules　provided　sufficient　adsorption　sites　for　a　high　enzyme　loading　capacity　of　102.79　mg　g−1,　as　well　as　abundant　and　shorter　substrate　transfer　pathways,　resulting　in　catalytic　efficiency　of　133.0　%　that　of　free　LDH.　TLS　capsules　achieved　an　optimal　balance　between　substrate　enrichment　and　diffusion　at　a　30　mmol　L−1　Na2SiO3　solution　concentration,　resulting　in　a　14　%　increase　in　catalytic　activity.　Furthermore,　the　mineralized　silica　layer　provided　suitable　enzyme-carrier　interactions,　ensuring　the　structural　stability　of　the　enzyme　under　extreme　conditions.　TLS　capsules　maintained　over　80.47　%　relative　activity　after　eight　cycles.　Our　work　broadens　the　scope　for　developing　and　applying　enzyme　immobilization　platforms.　©　2025　Elsevier　Ltd

Keyword：

Biocatalysis Capsules Conjugated polymer Enzyme immobilization Lactate dehydrogenase Silica

Community：

[ 1 ] [Wang Y.]School of Environment Science and Engineering, Tianjin University, Tianjin, 300072, China
[ 2 ] [Wang Y.]College of Chemical Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
[ 3 ] [Wang Y.]Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Fuzhou, Binhai New City, 350207, China
[ 4 ] [Wang Y.]Haihe Laboratory of Sustainable Chemical Transformations, Tianjin, 300192, China
[ 5 ] [Shi J.]School of Environment Science and Engineering, Tianjin University, Tianjin, 300072, China
[ 6 ] [Shi J.]Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Fuzhou, Binhai New City, 350207, China
[ 7 ] [Shi J.]Haihe Laboratory of Sustainable Chemical Transformations, Tianjin, 300192, China
[ 8 ] [Wu Z.]School of Environment Science and Engineering, Tianjin University, Tianjin, 300072, China
[ 9 ] [Wu Z.]Haihe Laboratory of Sustainable Chemical Transformations, Tianjin, 300192, China
[ 10 ] [Li W.]Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China
[ 11 ] [Li W.]Haihe Laboratory of Sustainable Chemical Transformations, Tianjin, 300192, China
[ 12 ] [Liu X.]School of Environment Science and Engineering, Tianjin University, Tianjin, 300072, China
[ 13 ] [Liu X.]Haihe Laboratory of Sustainable Chemical Transformations, Tianjin, 300192, China
[ 14 ] [Yang C.]College of Chemical Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
[ 15 ] [Yang C.]Engineering Research Center of Reactive Distillation, Fuzhou Province Higher Education Institutes, Fujian, Fuzhou, 350108, China
[ 16 ] [Qiu T.]College of Chemical Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
[ 17 ] [Qiu T.]Engineering Research Center of Reactive Distillation, Fuzhou Province Higher Education Institutes, Fujian, Fuzhou, 350108, China
[ 18 ] [Jiang Z.]Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Fuzhou, Binhai New City, 350207, China
[ 19 ] [Jiang Z.]Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China
[ 20 ] [Jiang Z.]Haihe Laboratory of Sustainable Chemical Transformations, Tianjin, 300192, China

Reprint 's Address：

Email：

Show more details

Related Keywords：

Conjugated polymer/enzyme/silica hybrid capsules for lactate biosynthesis
2025，Chemical Engineering Science
Catalytic Degradation of Chlorinated Lignin in Pulp Bleaching Wastewater over Immobilized Laccase
2022，SAINS MALAYSIANA
Conjugated microporous polymers-scaffolded enzyme cascade systems with enhanced catalytic activity
2024，Chinese Journal of Catalysis
Oxidative removal of phenol by HRP-immobilized beads and its environmental toxicology assessment
2016，ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
Biochemical and structural insights into an Ochrobactrum sp. CSL1 ribose-5-phosphate isomerase A and its roles in isomerization of rare sugars
2020，ENZYME AND MICROBIAL TECHNOLOGY

Source ：

Chemical Engineering Science

ISSN： 0009-2509

Year： 2025

Volume： 310

4 . 1 0 0

JCR@2023

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count：

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 0

Affiliated Colleges：

Get Fulltext

DOI Library Discovery Baidu Scholar Search SCOPUS

Type
Departments

All Years Choose Year From to