This　review　focuses　on　selected　examples　of　multiloaded　quantum-dot　(QD)　nanocomposites　as　novel　concepts　and　promising　labels　for　bioimaging　and　analysis.　As　bright,　excellent,　10-nm-sized　labels,　providing　high-intensity　signal,　QDs　can　reach　higher　levels　when　multiloaded　into　a　single　biocompatible　nanocontainer.　QD-containing　nanocomposites　combine　the　properties　of　both　materials　(i.e.,　luminescent　and　electrochemical　characteristics　of　the　entrapped　QDs　and　permeability,　solubility,　reactivity　or　biocompatibility　of　the　carrier).　Approaches　described　include　multiple　QD-containing　nanocomposites　with　different　carriers　organic　(dendrimers　and　layer-by-layer　hollow　microcapsules),　inorganic　(carbon　nanotubes　and　silica　nanoparticles)　and　of　a　combined　nature.　We　also　consider　and　discuss　promising　applications　in　bioanalysis.　(C)　2014　Elsevier　B.V.　All　rights　reserved.