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author:

史迎莹 (史迎莹.) [1] | 严芬 (严芬.) [2] | 赵冠杰 (赵冠杰.) [3] | 郭养浩 (郭养浩.) [4] (Scholars:郭养浩)

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CQVIP PKU CSCD

Abstract:

通过比较不同类型阴离子交换树脂的吸附性能,筛选出对(R)-扁桃酸富集率高、杂质吸附率较低的H401阴离子交换树脂.最适动态吸附条件为:上柱液pH 6.0~6.5,流速1.0B(V-)/h;最适动态洗脱条件为:洗脱液为1.0%盐酸,洗脱流速0.5B(V-)/h.优化条件下,发酵液中(R)-扁桃酸的总提取率为95%,最终产物的纯度达95%,ee值98.5%.

Keyword:

(R)-扁桃酸 分离纯化 发酵液 离子交换

Community:

  • [ 1 ] [史迎莹]福州大学
  • [ 2 ] [严芬]福州大学
  • [ 3 ] [赵冠杰]福州大学
  • [ 4 ] [郭养浩]福州大学

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Source :

中国医药工业杂志

ISSN: 1001-8255

CN: 31-1243/R

Year: 2007

Issue: 8

Volume: 38

Page: 555-557

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 5

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