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Abstract:
Treatment temperature distribution is a crucial factor for magnetic hyperthermia, since it directly determines the treatment effect related to the apoptosis situation of malignant cells. The shape of magnetic nanoparticles (MNPs) is one of many factors that can affect the treatment temperature during therapy. This paper conducts a comparative study on three different shapes of MNPs by considering the effective area percentage of treatment temperature distribution. The treatment temperature for a proposed model is predicted by solving bio-heat transfer equations, which take the power dissipation of MNPs as the input and consider a temperature-dependent blood perfusion rate in these equations at the same time. The simulation results demonstrate that the treatment temperature distribution can be effectively improved when the temperature-dependent blood perfusion rate is used for the simulation with respect to a constant case. In addition, the MNPs with higher regular shape can lead to a better result than a lower case in the treatment temperature distribution when the same condition is considered for therapy.
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JOURNAL OF PHYSICS D-APPLIED PHYSICS
ISSN: 0022-3727
Year: 2021
Issue: 16
Volume: 54
3 . 4 0 9
JCR@2021
3 . 1 0 0
JCR@2023
ESI Discipline: PHYSICS;
ESI HC Threshold:87
JCR Journal Grade:2
CAS Journal Grade:3
Cited Count:
WoS CC Cited Count: 9
SCOPUS Cited Count:
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 1