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author:

Tang, Yundong (Tang, Yundong.) [1] (Scholars:汤云东) | Flesch, Rodolfo C. C. (Flesch, Rodolfo C. C..) [2] | Jin, Tao (Jin, Tao.) [3] (Scholars:金涛) | Gao, Yueming (Gao, Yueming.) [4] (Scholars:高跃明) | He, Minhua (He, Minhua.) [5]

Indexed by:

EI SCIE

Abstract:

Treatment temperature distribution is a crucial factor for magnetic hyperthermia, since it directly determines the treatment effect related to the apoptosis situation of malignant cells. The shape of magnetic nanoparticles (MNPs) is one of many factors that can affect the treatment temperature during therapy. This paper conducts a comparative study on three different shapes of MNPs by considering the effective area percentage of treatment temperature distribution. The treatment temperature for a proposed model is predicted by solving bio-heat transfer equations, which take the power dissipation of MNPs as the input and consider a temperature-dependent blood perfusion rate in these equations at the same time. The simulation results demonstrate that the treatment temperature distribution can be effectively improved when the temperature-dependent blood perfusion rate is used for the simulation with respect to a constant case. In addition, the MNPs with higher regular shape can lead to a better result than a lower case in the treatment temperature distribution when the same condition is considered for therapy.

Keyword:

blood perfusion rate magnetic hyperthermia nanoparticles shape therapeutic temperature distribution

Community:

  • [ 1 ] [Tang, Yundong]Fuzhou Univ, Coll Phys & Informat Engn, Fuzhou 350116, Peoples R China
  • [ 2 ] [Gao, Yueming]Fuzhou Univ, Coll Phys & Informat Engn, Fuzhou 350116, Peoples R China
  • [ 3 ] [Flesch, Rodolfo C. C.]Univ Fed Santa Catarina, Dept Automacao & Sistemas, BR-88040900 Florianopolis, SC, Brazil
  • [ 4 ] [Jin, Tao]Fuzhou Univ, Coll Elect Engn & Automat, Fuzhou 350116, Peoples R China
  • [ 5 ] [Gao, Yueming]Key Lab Med Instrumentat & Pharmaceut Technol Fuj, Fuzhou 350108, Fujian, Peoples R China
  • [ 6 ] [He, Minhua]Fujian Med Univ, Fuzhou 350122, Fujian, Peoples R China

Reprint 's Address:

  • 汤云东

    [Tang, Yundong]Fuzhou Univ, Coll Phys & Informat Engn, Fuzhou 350116, Peoples R China

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Source :

JOURNAL OF PHYSICS D-APPLIED PHYSICS

ISSN: 0022-3727

Year: 2021

Issue: 16

Volume: 54

3 . 4 0 9

JCR@2021

3 . 1 0 0

JCR@2023

ESI Discipline: PHYSICS;

ESI HC Threshold:87

JCR Journal Grade:2

CAS Journal Grade:3

Cited Count:

WoS CC Cited Count: 9

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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